Hyperbaric Oxygen Therapy
Regenexx Las Vegas offers up to a 2ATA multiplace hardshell hyperbaric oxygen chamber for healing, wellness, and recovery. Hyperbaric oxygen therapy is a non-invasive medical treatment that involves breathing pure oxygen in a pressurized chamber. Multiplace hyperbaric chambers are larger chambers that can accommodate more than one person at a time. This can help reduce the feeling of claustrophobia that can happen more often in smaller monochambers.
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How it Works
During hyperbaric oxygen therapy, patients breathe pure oxygen while inside a hyperbaric chamber. The increased pressure in the chamber allows the lungs to absorb more oxygen, which is then delivered to all parts of the body. This increased oxygen delivery helps to promote healing, reduce inflammation, and boost the immune system.
The number of sessions needed can vary depending on the condition but can range from 3-40 depending on the goals of treatment. Each treatment can last 60-90 minutes. The pressure will range from 1.5 to 2 ATA depending on the condition.
HBOT leads to…
- Increased oxygen to the body’s tissues up to 25 times the normal amount, thereby reversing hypoxia
- Strengthened immune system
- New blood vessel growth
- Increased production of stem cells
- Increased wound healing and damaged tissue
- Reduction of inflammation, swelling, and edema
- Anti-microbial/microbiome balancing
- Increased energy and reduces fatigue
- Reversal of traumatic and ischemic brain and nerve injuries
- Optimized wound healing
Reasons to Consider Hyperbaric Oxygen Therapy
Pre/Post Regenerative injections
(PRP, bone marrow concentrate which contains stem cells)
Hyperbaric oxygen therapy is gaining attention as an adjunctive therapy for pre and post Platelet-Rich Plasma (PRP) and bone marrow concentrate (BMC) injections. It is thought to help by enhancing tissue oxygenation, controlling inflammation and potentially accelerating angiogenesis and collagen production. HBOT may contribute to faster recovery and improved pain management following PRP and BMC injections. By promoting tissue healing, reducing inflammation, and enhancing cellular function, HBOT can potentially speed up the recovery process and alleviate pain associated with musculoskeletal injuries/conditions.
SAMPLE Pre-surgical Treatment Protocol: (Based on the available studies. Some people may need more or less treatments or different pressure based on their individual condition and treatment response)
- Pressure: 2 ATA
- Sessions: 3-5 sessions daily immediately prior to injection therapy
- Duration: 90 minutes
- Pressure: 2 ATA
- Sessions: 10 sessions daily immediately post injection therapy, with some going up to 20 sessions post injection (3-4 sessions per week)
- Duration: 60 minutes
- Botha D M. The effect of hyperbaric oxygen and blood platelet injection therapy on healing of hamstring injuries in rugby players: A case series report. AJPHERD. November 2015; (supplement 1), 29-39.
- Thorn S, Bhopale V, Velazquez O, Goldstein L, Thorn L, and Buerk D. Stem cell mobilization by hyperbaric oxygen. Am J Physiol Heart Circ Physiol 290: H1378-H1386
Pre/post-surgical optimization
Hyperbaric oxygen therapy can be used both before and after surgery to promote healing and reduce the risk of complications. Before surgery, hyperbaric oxygen therapy can help prepare the body for the upcoming procedure by improving circulation, reducing inflammation, and increasing the production of growth factors. After surgery, hyperbaric oxygen therapy can help speed up the healing process, reduce pain and swelling, and minimize the risk of infection.
SAMPLE Pre-surgical Treatment Protocol: Based on the available studies. Some people may need more or less treatments based on their individual responses.
- Pressure: 2 ATA
- Sessions: 3-5 sessions daily immediately prior to surgery
- Duration: 90 minutes
- Pressure: 2 ATA
- Sessions: 10 sessions (will vary depending on the condition)
- Duration: 60-90 minutes
- Gao Zhi-xin et al. Hyperbaric oxygen preconditioning improves postoperative cognitive dysfunction by reducing oxidant stress and inflammation. Neural Regen Res. 2017 Feb; 12(2): 329-336
- Friedman, T et al. Hyperbaric Oxygen Preconditioning Can Reduce Postabdominoplasty Complications: A retrospective Cohort Study. Plast Reconstr Surg Glob Open. Oct 2019. V.7 (10);
- Larsson A et al. Hyperbaric oxygen in the treatment of postoperative infections in paediatric patients with neuromuscular spine deformity. Eur Epine J, 2011 Dec 20(12) 2217-2222
- Bosco G, Casarotto A, Nasole E, et al. Preconditioning with hyperbaric oxygen in pancreaticoduodenectomy: a randomized double-blind pilot study. Anticancer Res 2014; 34:2899–2906.
- Li Y, Dong H, Chen M, et al. Preconditioning with repeated hyperbaric oxygen induces myocardial and cerebral protection in patients undergoing coronary artery bypass graft surgery: a prospective, randomized, controlled clinical trial. J Cardiothorac Vasc Anesth 2011; 25:908–916.
- Perrins D, Cantab M. Influence of hyperbaric oxygen on the survival of split skin grafts. Lancet 1967; 1:868–871.
- Jeysen ZY, Gerard L, Levant G, et al. Research report: the effects of hyperbaric oxygen preconditioning on myocardial biomarkers of cardioprotection in patients having coronary artery bypass graft surgery. Undersea Hyperb Med 2018; 38:175–185.
Injury recovery
Hyperbaric oxygen therapy can also be used to aid in the recovery from various sports injuries, and traumatic brain injuries. The increased oxygen delivery to the affected area promotes tissue repair and can help reduce pain and swelling.
SAMPLE Treatment Protocol: (Based on the available studies. Some people may need more or less treatments based on their individual condition and treatment response)
- Pressure: 2 ATA
- Sessions: 10-20 hours: will vary depending on the situation.
- Duration: 60-90 minutes
- Barata, P. Hyperbaric oxygen effects on Sports injuries. Ther Adv Musculoskel Dis. 2011; 3(2) 111-121
- Botha D M. The effect of hyperbaric oxygen and blood platelet injection therapy on healing of hamstring injuries in rugby players: A case seriesreport. AJPHERD. November 2015; (supplement 1), 29-39.
Wellness/Biohacking
In addition to its medical uses, hyperbaric oxygen therapy is also used for wellness purposes, such as anti-aging, improved athletic performance, and stress reduction. The increased oxygen delivery to the body can help improve energy levels, reduce fatigue, and enhance overall well-being.
SAMPLE Treatment Protocol: (Based on the available studies. Some people may need more or less treatments based on their individual condition and treatment response)
- Pressure: 1.5-2 ATA
- Sessions: at least 20 sessions and up to 60 then intermittently: sessions 2-3 times weekly (depends on goals and response)
- Duration: 60-90 minutes
- Thorn S, Bhopale V, Velazquez O, Goldstein L, Thorn L, and Buerk D. Stem cell mobilization by hyperbaric oxygen. Am J Physiol Heart Circ Physiol 290: H1378-H1386
- Gottfried I, Schottlender N, Ashery U. Hyperbaric Oxygen Treatment-From Mechanisms to Cognitive Improvement. Biomolecules. 2021 Oct 15;11(10):1520.
Fibromyalgia pain
Fibromyalgia is a complex chronic pain condition characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and tenderness in specific areas of the body. It is believed to be a disorder of the central nervous system, resulting in amplified pain signals and increased sensitivity to stimuli.
SAMPLE Treatment Protocol: (Based on the available studies. Some people may need more or less treatments based on their individual condition and treatment response)
- Pressure: 2 ATA
- Sessions: 40
- Duration: 90 minutes
References:
- Efrati, S et al. Hyperbaric Oxygen Therapy Can Diminish Fibromyalgia Syndrome – Prospective Clinical Trial. PLoS One 2015; 10(5): e0127012
- Chen X, You J, Ma H, et al Efficacy and safety of hyperbaric oxygen therapy for fibromyalgia: a systematic review and meta-analysis BMJ Open 2023;13:e062322
Painful peripheral neuropathy
Painful peripheral neuropathy is a condition characterized by damage to the peripheral nerves, leading to tingling, burning, and shooting pain in the extremities.
SAMPLE Treatment Protocol: (Based on the available studies. Some people may need more or less treatments based on their individual condition and treatment response)
- Pressure: 2 ATA
- Sessions: 24-36 sessions (2-3 x per week x 3 months)
- Duration: 90 minutes
References:
- Liu, YD et al. Hyperbaric oxygen treatment attenuates neuropathic pain by elevating autophagy flux via inhibiting mTOR pathway. AM J Transl Res. 2017, 9(5): 2629-2638
- Brenna CT, Khan S, Katznelson R, et al The role of hyperbaric oxygen therapy in the management of perioperative peripheral nerve injury: a scoping review of the literature Regional Anesthesia & Pain Medicine Published Online First: 23 November 2022
- Schiavo S, DeBacker J, Djaiani C, Bhatia A, Englesakis M, Katznelson R. Mechanistic Rationale and Clinical Efficacy of Hyperbaric Oxygen Therapy in Chronic Neuropathic Pain: An Evidence-Based Narrative Review. Pain Res Manag. 2021 Apr 22;2021:8817504. doi: 10.1155/2021/8817504. PMID: 33976752; PMCID: PMC8084668.
Long Covid symptoms
Long COVID refers to a condition where individuals continue to experience persistent symptoms and health issues for weeks or months after recovering from the acute phase of COVID-19.
SAMPLE Treatment Protocol: (Based on the available studies. Some people may need more or less treatments based on their individual condition and treatment response)
- Pressure: 1.5-2 ATA
- Sessions: 10 sessions over 12 days but could be as much as 40 treatments (3-5 weekly sessions) over a 2-3 months.
- Duration: 90 minutes
References:
- Zilberman-Itskovich S, Catalogna M, Sasson E, Elman-Shina K, Hadanny A, Lang E, Finci S, Polak N, Fishlev G, Korin C, Shorer R, Parag Y, Sova M, Efrati S. Hyperbaric oxygen therapy improves neurocognitive functions and symptoms of post-COVID condition: randomized controlled trial. Sci Rep. 2022 Jul 12;12(1):11252
- Robbins T, Gonevski M, Clark C, Baitule S, Sharma K, Magar A, Patel K, Sankar S, Kyrou I, Ali A, Randeva HS. Hyperbaric oxygen therapy for the treatment of long COVID: early evaluation of a highly promising intervention. Clin Med (Lond). 2021 Nov;21(6):e629-e632.
- Kjellberg A, Abdel-Halim L, Hassler A, El Gharbi S, Al-Ezerjawi S, Boström E, Sundberg CJ, Pernow J, Medson K, Kowalski JH, Rodriguez-Wallberg KA, Zheng X, Catrina S, Runold M, Ståhlberg M, Bruchfeld J, Nygren-Bonnier M, Lindholm P. Hyperbaric oxygen for treatment of long COVID-19 syndrome (HOT-LoCO): protocol for a randomised, placebo-controlled, double-blind, phase II clinical trial. BMJ Open. 2022 Nov 2;12(11)
- Boet S., Etherington C., Djaiani G., Tricco A.C., Sikora L., Katznelson R. Efficacy and safety of hyperbaric oxygen treatment in SARS-CoV-2 (COVID-19) pneumonia: A systematic review. Diving Hyperb. Med. 2021;51:271–281.
Chronic Fatigue Syndrome
Chronic Fatigue Syndrome (CFS) is a complex, long-term illness characterized by extreme fatigue that doesn't improve with rest and worsens with physical or mental activity.
SAMPLE Treatment Protocol: (Based on the available studies. Some people may need more or less treatments based on their individual condition and treatment response)
- Pressure: 2 ATA
- Sessions: 15 sessions over a 4 weeks period
- Duration: 60 minutes
References:
- Akarsu S, Tekin L, Ay H, Carli AB, Tok F, Simşek K, Kiralp MZ. The efficacy of hyperbaric oxygen therapy in the management of chronic fatigue syndrome. Undersea Hyperb Med. 2013 Mar-Apr;40(2):197-200
Other HBOT Protocols
HEALTHY AGING
An intensive dose of hyperbaric oxygen therapy to assist with providing oxygen support to all organ systems. Best when combined with good nutrition, supplements and regular exercise.
•FREQUENCY: Daily — 60 sessions
•VARIABLE PRESSURE: 1.3 ATA – 2.0 ATA
•DURATION: 110 minutes
GENTLE SUPPORT
Unwind and let go with this protocol designed to reduce stress, alleviate tension, and prepare you for a restful night’s sleep. This gentle approach to hyperbaric oxygen therapy is perfect for those looking to relax and rejuvenate. This protocol is an excellent way to prepare yourself for a restful night’s sleep while also reducing stress and tension. Ideal for those who are looking for a softer, more relaxing hyperbaric experience
•FREQUENCY: PRN (as needed)
•VARIABLE PRESSURE: 1.3 ATA – 1.5 ATA
•DURATION: 75 minutes
CHRONIC HEALTH SUPPORT
This is a standard hyperbaric protocol that provides a surplus of oxygen to your body and in return gives a wealth of physiologically available oxygen to give yourself the best opportunity for self healing and recovery.
•FREQUENCY: Daily — 40 sessions
•VARIABLE PRESSURE: 1.5 ATA – 2.0 ATA
•DURATION: 80 minutes
INJURY RECOVERY
This protocol was created for those suffering from acute injuries that include inflammation, pain, and loss of function due to the nature of the injury.
•FREQUENCY: Daily — 10 sessions
•VARIABLE PRESSURE: 1.5 ATA – 2.0 ATA
•DURATION: 75 minutes
CHRONIC CONSUSSION
Post concussive syndrome, long standing TBI symptoms — 40 sessions, daily. For best results, try and complete within 2-3 months and rest for 3 hours after each session oxygen to give yourself the best opportunity for self healing and recovery
•FREQUENCY: Daily — 40 sessions
•VARIABLE PRESSURE: 1.5 ATA – 2.0 ATA
•DURATION: 80 minutes
PRECONDITIONING
3-5 sessions, daily or every other day, with final session to be applied the day before the planned event (ie sporting event, surgery, etc)
•FREQUENCY: 3-5 sessions
•VARIABLE PRESSURE: 1.5 ATA – 2.0 ATA
•DURATION: 75 minutes
EXERCISE RECOVERY
Use this protocol after an intense workout, game, or physical activity and help your body speed up recovery and tackle areas of injury, pain, and inflammation before they become an issue.
•FREQUENCY: PRN (as needed)
•VARIABLE PRESSURE: 1.5 ATA – 2.0 ATA
•DURATION: 50 minutes
RECHARGE
Take a break while enjoying the benefits of a restful oxygen session. Perfect for that afternoon break, during a high-stress day, or for that quick daytime boost in energy
•FREQUENCY: PRN (as needed)
•VARIABLE PRESSURE: 1.3 ATA – 1.5 ATA
•DURATION: 45 minutes
Josh Goodwin, MD, FAAPMR
Step into our state-of-the-art hardshell 2 ATA multiplace hyperbaric chamber, where comfort meets relaxation.
Contact Regenexx Las Vegas today at 702.986.0921 to learn more about how hyperbaric oxygen therapy can help you achieve your health and wellness goals.
Frequently Asked Questions
How does Hyperbaric oxygen therapy work?
Essentially, hyperbaric oxygen treatments use a combination of elevated ambient pressure and inspired oxygen concentration to greatly increase the amount of oxygen in the blood. This elevated oxygen concentration allows oxygenation of tissues that are not getting enough oxygen at baseline, encourages new blood vessels to grow into these oxygen-deprived tissues.
What happens when I come in for a consultation?
Each patient's experience will be somewhat different, but in general, the following events will occur:
- You will be seen by the physician who will perform a history and physical. He or she will determine if hyperbaric treatments are appropriate for you, order any necessary tests, and discuss the treatment options.
What happens during a hyperbaric oxygen therapy treatment?
There are several stages during a typical treatment:
- The first stage is compression in which the chamber is pressurized to the prescribed pressure. This pressure will be different depending on the condition. Our machine goes up to 2 ATA (33 feet of seawater).
- During this phase, patients can feel pressure in the ears. If there is any trouble clearing the ears, the patient has full control internally to slow down the pressurization process.
- Given that our chamber is a multiplace chamber, it is pressurized with air and the person breathes in up to 100% oxygen through a mask or hood.
- The chamber is maintained at the prescribed pressure while the patient breathes the oxygen through the mask or hood.
- After the oxygen period is finished, the chamber is depressurized, and the treatment is finished.
How long does an HBOT session last?
The duration of an HBOT session can vary depending on the condition being treated. Typically, sessions last about 60-120 minutes.
How many treatments will I need and how often?
This depends on the condition being treated. For example, a pre-surgical optimization program may include daily sessions for 3-5 days immediately prior to surgery, while other wellness or biohacking programs may include up to 40 sessions spread out a few times a week taking a few months to complete.
Is HBOT covered by insurance?
Insurance coverage for HBOT depends on the condition being treated and the specific health insurance policy. There are some “on label” conditions that do have coverage. But the above noted “off label” conditions do not currently have insurance coverage.
How much does each session of HBOT therapy cost?
The cost for HBOT sessions:
- 60 minutes up to 2 ATA is $150/session
- 90 minutes up to 2 ATA is $200/session
- There are discounts for those that purchase multi-session packages or when combined with other services.
What are the contraindications to HBOT?
Contraindications to HBOT:
- Absolute contraindication:
- Untreated pneumothorax
- Relative contraindication:
- Concurrent HBOT and certain chemotherapy drugs
- Doxorubicin, Bleomycin, Disulfiram, Mafenide
- COPD: (May need x-ray)
- Asthma: Uncontrolled
- Implanted devices: Check with the manufacturer
- Epidural pain pumps
- Pregnancy
- Epilepsy if uncontrolled
- Inability to equalize ears or sinus pressure
- Recent Eye surgery
- Recent thoracic surgery
- Current upper respiratory illness
- Insulin-dependent diabetes: Blood glucose needs to be monitored as HBOT can cause hypoglycemia
- History of Tuberculosis
- Concurrent HBOT and certain chemotherapy drugs
What are the risks of hyperbaric chamber treatment?
- Ear and Sinus Problems: Due to the increased air pressure, patients might experience ear pain or a feeling of fullness in the ears. In rare cases, this can lead to ear drum rupture. Sinus pain can also occur. Precautions like ear clearing techniques can help reduce this risk. In our chamber, the patient also has the ability to control the pressurization if starts to feel pressure in the ears. A push of a button slows down the pressurization to allow more time for the person to acclimate to the increasing pressure.
- Temporary Vision Changes: Some patients may experience changes in vision during their treatment course. These changes are usually temporary and resolve after the treatment is completed. For those with cataracts, HBOT has the potential to mature the cataracts which can make them worse. It is important to bring up history of cataracts prior to moving forward with HBOT.
- Claustrophobia: The enclosed space of the chamber can trigger claustrophobia in some individuals. Our multiplace chamber reduces the feeling of claustrophobia due to the larger size. Patients also can feel more at ease given the internal controls if needed to exit the chamber due to claustrophobia.
- Oxygen Toxicity: While rare (<1%) , prolonged exposure to high levels of oxygen can lead to oxygen toxicity, affecting the lungs and central nervous system. There are two types of oxygen toxicity: central and pulmonary. The pressure and duration of treatment has influence on the risk of toxicity. HBOT protocols are designed to minimize these risks by controlling the duration of exposure and the concentration of oxygen used.
- Central Nervous System Oxygen Toxicity: CNS oxygen toxicity occurs when a high concentration of oxygen is absorbed by the central nervous system. This can lead to symptoms such as visual disturbances (like tunnel vision), ear ringing, nausea, twitching (especially facial twitching), irritability, dizziness, and in severe cases, seizures. CNS toxicity is more likely to occur during HBOT due to the high levels of oxygen at increased atmospheric pressure. The risk increases with longer exposure times and higher oxygen pressures.
- Pulmonary Oxygen Toxicity: Pulmonary oxygen toxicity impacts the lungs and is associated with prolonged exposure to high concentrations of oxygen. It can cause symptoms like a mild cough, chest pain (under the breastbone), and difficulty breathing. In severe cases, it can lead to lung damage, characterized by inflammation and scarring of lung tissue (fibrosis). This form of oxygen toxicity is more gradual and typically occurs after prolonged periods of exposure to elevated oxygen levels, such as those encountered in HBOT at high pressures and long durations. Not typically seen in treatment pressure of 2ATA or less or 60–90-minute sessions.
- Pulmonary Barotrauma: This is a risk if air pockets exist in the body, potentially leading to collapsed lungs. This is very rare at pressures of 1.5 to 2 ATA.
- Low Blood Sugar: Diabetic patients may experience a drop in blood sugar levels during treatment.
- Fatigue and Headaches: These are relatively common but typically mild side effects, often resolving soon after the treatment.
How long after the HBOT session can I fly?
You should not fly for 24 hours after an HBOT session.
Should I take antioxidants prior to HBOT session?
It depends. Most people will not need to use antioxidants. There are some that may be sensitive to the oxidation caused by the increased oxygen supplied to the body during HBOT treatment. If one feels extra fatigue or headaches that persist, then can pre-treat or post-treat with antioxidants 30 minutes prior to or after the HBOT session.
What should I wear?
We will change every patient into a medical gown and paper shorts to sit in the chamber. Other options are light-colored cotton shirt and sweat pants or shorts.
How is the oxygen supplied in the chamber?
The chamber is pressurized with air and the oxygen is delivered via a mask worn throughout the session. Each person will have their own mask.